If you’ve been exploring regenerative aesthetics, you’ve likely come across the terms PRP, PRF, and EZgel. All three are natural, injectable treatments derived from your own blood, and all three support skin rejuvenation and collagen production. But they are not the same treatment, and the differences between them matter more than most people realize. Understanding how each one works can help you make a more informed decision about which approach is right for your skin goals.
At Bare Radiance Aesthetics, we offer PRF and PRF EZgel treatments for clients throughout Broomfield, Arvada, Erie, Westminster, and the surrounding communities in Colorado.
What Do PRP, PRF, and EZgel Have in Common?
All three treatments are classified as autologous therapies, meaning they are created entirely from your own blood. A small sample is drawn at the start of your appointment and processed in a centrifuge to concentrate the beneficial components, including platelets, growth factors, and, in some cases, white blood cells and stem cells. Because nothing synthetic is introduced into the body, these treatments carry a minimal risk of adverse reactions and work in harmony with your body’s natural healing processes.
Where they diverge is in how they are processed, what they retain, and what they are best designed to treat.
PRP: Platelet-Rich Plasma
PRP is the oldest and most widely recognized of the three. Blood is spun at high speeds in a centrifuge and combined with an anticoagulant, which isolates the plasma and platelets while removing most white blood cells and stem cells. The result is a highly liquid concentrate that releases its growth factors quickly.
Because of its fluid consistency and rapid release, PRP is best suited for scalp injections to support hair restoration and for topical application during microneedling treatments. It is less commonly used for facial volume. Results from PRP typically last three to six months.
PRF: Platelet-Rich Fibrin
PRF represents a meaningful advancement over PRP. The key difference lies in the processing: blood is spun at lower speeds and without any anticoagulant additives. This gentler approach preserves a richer concentration of white blood cells, stem cells, and a natural fibrin network within the sample.
That fibrin network acts as a slow-release scaffold, gradually delivering growth factors to the treated tissue over days and even weeks after injection. The result is stronger, more sustained collagen stimulation and improved overall tissue quality compared to PRP. PRF is well-suited for treating deeper lines, delicate facial areas, and under-eye concerns. Results typically last nine to twelve months.
PRF EZgel: The Natural Filler Alternative
EZgel takes PRF one step further. After the low-speed centrifuge process, the plasma portion is gently heated and then cooled, transforming the liquid PRF into a smooth, gel-like consistency with no synthetic ingredients whatsoever. The result is a 100% natural, biocompatible gel that closely mimics the behavior of a traditional dermal filler.
This makes EZgel particularly effective for hollow or delicate areas where volume loss is most visible, especially the under-eye area. For patients searching for a PRF under-eye treatment in Erie, CO, or the surrounding communities, EZgel offers a compelling option: immediate plumping from the gel itself, combined with ongoing cellular regeneration as the growth factors continue working beneath the surface. Results from EZgel typically last twelve to eighteen months after a series of three.
Side-by-Side Comparison
Consistency
PRP: Liquid
PRF: Liquid
EZgel: Thick, gel-like
Processing
PRP: High-speed spin with anticoagulant
PRF: Low-speed spin, no additives
EZgel: Low-speed spin, then heated and cooled
Growth Factor Release
PRP: Fast release
PRF: Slow, sustained release
EZgel: Scaffolded volume plus slow release
Best For
PRF: Skin rejuvenation, fine lines, delicate areas, microneedling
EZgel: Under-eye hollows, volume loss, natural filler alternative
Results Duration
PRP: 3 to 6 months
PRF: 9 to 12 months
EZgel: 12 to 18 months
Which Treatment Is Right for You?
The right choice depends on your specific concerns and what you hope to achieve. Patients dealing with under-eye hollows, dark circles, or subtle volume loss tend to see excellent results with PRF EZgel. Those focused on overall skin quality, fine lines, and collagen support post microneedling often benefit most from PRF.
Many patients find that combining treatments delivers the most comprehensive results. During your consultation at Bare Radiance Aesthetics, your provider will evaluate your skin, discuss your goals, and recommend the approach best suited to your unique anatomy.
Frequently Asked Questions About PRF and EZgel
Are PRF and EZgel safe?
Yes. Because both treatments are made entirely from your own blood, the risk of allergic reaction or rejection is extremely low. There are no synthetic chemicals or foreign substances involved.
How many treatment sessions will I need?
Many patients achieve their desired outcome with a series of three. Your provider will outline a personalized plan during your consultation.
Is there downtime after PRF or EZgel treatment?
Downtime is minimal. Some patients experience mild swelling, redness, or bruising at the injection site, but most can return to their normal activities within a day or two.
How soon will I see results from PRF EZgel?
With EZgel, some volume improvement is visible shortly after treatment as the gel itself provides an immediate plumping effect. The regenerative benefits, including new collagen production, continue to develop over the following weeks and months.
Can PRF or EZgel be combined with other treatments?
Yes. PRF and EZgel pair well with other services such as Botox, Dysport, or traditional dermal fillers to create a comprehensive treatment plan. Your injector can help determine which combination best addresses your goals.
Experience Regenerative Aesthetics at Bare Radiance in Broomfield, CO
At Bare Radiance Aesthetics, our skilled team is proud to offer advanced PRF and PRF EZgel treatments for clients throughout Broomfield, Erie, Westminster, Louisville, Thornton, and the greater Denver area. Whether you’re exploring a PRF under-eye treatment in Erie, CO, looking to improve overall skin quality, or curious about natural alternatives to traditional filler, we’re here to help you find the right solution.
Schedule your complimentary consultation today and discover what regenerative aesthetics can do for your skin.